Visfatin
Visfatin (NAMPT / PBEF)
An adipokine with insulin-mimetic properties and a key role in NAD+ biosynthesis. Has complex effects on metabolism and inflammation.
Mechanism of Action
Visfatin (NAMPT) is the rate-limiting enzyme in NAD+ biosynthesis. It also has extracellular insulin-mimetic effects via insulin receptor binding. It modulates inflammation and has complex metabolic effects.
Health Claims & Evidence
Insulin-mimetic effects
Key role in NAD+ biosynthesis
Modulates inflammation
Short-Term Effects
Insulin-like effects, NAD+ pathway modulation.
Long-Term Effects
Research use primarily.
Side Effects
Complex pro- and anti-inflammatory effects.
Contraindications
Research use only.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Visfatin and insulin mimicry
Fukuhara et al. · Science · 2005
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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