Chemerin
Chemerin (RARRES2)
An adipokine and chemokine that recruits immune cells to adipose tissue and modulates inflammation and metabolism.
Mechanism of Action
Chemerin binds to CMKLR1, GPR1, and CCRL2 receptors, recruiting NK cells, dendritic cells, and macrophages to adipose tissue. It modulates adipogenesis and has complex metabolic effects.
Health Claims & Evidence
Modulates adipose tissue inflammation
Regulates adipogenesis
Biomarker for metabolic syndrome
Short-Term Effects
Immune cell recruitment, inflammation modulation.
Long-Term Effects
Research use primarily.
Side Effects
Inflammatory effects.
Contraindications
Research use only.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Chemerin and adipose tissue inflammation
Bozaoglu et al. · Endocrinology · 2007
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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