FGF-2
Fibroblast Growth Factor 2 (Basic FGF)
A potent angiogenic and wound-healing growth factor. Promotes blood vessel formation, tissue repair, and neuroprotection.
Mechanism of Action
FGF-2 binds to FGFR receptors, activating MAPK and PI3K pathways. It promotes angiogenesis, fibroblast proliferation, wound healing, and neuronal survival.
Health Claims & Evidence
Promotes angiogenesis and wound healing
Neuroprotective effects
Supports bone and cartilage repair
Short-Term Effects
Accelerated wound healing, angiogenesis promotion.
Long-Term Effects
Research use primarily.
Side Effects
Potential for tumor promotion with excessive angiogenesis.
Contraindications
Use with caution in individuals with active cancer.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
FGF-2 and angiogenesis
Folkman et al. · Science · 1987
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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