Recovery & Repair

SHH Peptide

Sonic Hedgehog Signaling Peptide

A peptide activator of the Sonic Hedgehog (SHH) signaling pathway. Promotes stem cell activation, hair follicle growth, and neuroprotection.

HedgehogStem CellHair GrowthNeuroprotectionRegeneration

Quick Reference

Category
Recovery & Repair
Research Claims
3 reviewed
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Mechanism of Action

SHH pathway activation promotes stem cell proliferation, hair follicle cycling, and neuronal survival. It activates Gli transcription factors that regulate tissue development and regeneration.

Health Claims & Evidence

Promotes hair follicle growth

ModerateSHH pathway activation promotes hair follicle cycling

Neuroprotective effects

ModerateSHH-mediated neuronal survival documented

Stem cell activation for tissue regeneration

Moderatestem cell proliferation via SHH documented

Short-Term Effects

Hair follicle activation, neuroprotection.

Long-Term Effects

Research use primarily.

Side Effects

Potential for tumor promotion with excessive SHH activation (basal cell carcinoma risk).

Contraindications

Use with caution — SHH pathway is oncogenic when dysregulated.

This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.

Research Papers

Sonic Hedgehog and hair follicle cycling

Oro et al. · Science · 1997

Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.

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