SCF
Stem Cell Factor (SCF / c-Kit Ligand)
A growth factor that activates c-Kit receptors on hematopoietic stem cells, mast cells, and melanocytes. Critical for hematopoiesis and melanocyte survival.
Mechanism of Action
SCF binds to c-Kit receptors, activating MAPK and PI3K pathways. It promotes hematopoietic stem cell survival and proliferation, mast cell activation, and melanocyte survival.
Health Claims & Evidence
Promotes hematopoietic stem cell survival
Supports melanocyte survival and pigmentation
Potential hair pigmentation support
Short-Term Effects
Stem cell mobilization, mast cell activation.
Long-Term Effects
Research use primarily.
Side Effects
Mast cell activation (allergic reactions), injection site reactions.
Contraindications
Use with caution in individuals with mast cell disorders.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
SCF and hematopoiesis
Zsebo et al. · Cell · 1990
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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