Meteorin-like
Meteorin-like (Metrnl / SUBFATIN)
An exercise and cold-induced hormone that promotes white adipose tissue browning, reduces inflammation, and improves insulin sensitivity.
Mechanism of Action
Meteorin-like is secreted from muscle during exercise and from adipose tissue during cold exposure. It activates eosinophils to produce IL-4, which promotes adipose tissue browning and thermogenesis.
Health Claims & Evidence
Promotes adipose tissue browning and thermogenesis
Reduces inflammation
Improves insulin sensitivity
Short-Term Effects
Potential metabolic improvements, anti-inflammatory effects.
Long-Term Effects
Research use primarily.
Side Effects
Limited human data.
Contraindications
Limited human safety data.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Meteorin-like and adipose browning
Rao et al. · Cell · 2014
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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