Adiponectin
Adiponectin (AdipoQ)
An adipokine with potent insulin-sensitizing, anti-inflammatory, and cardioprotective properties. Low levels are associated with obesity, diabetes, and cardiovascular disease.
Mechanism of Action
Adiponectin binds to AdipoR1 and AdipoR2 receptors, activating AMPK and PPAR-alpha pathways. This improves insulin sensitivity, reduces hepatic glucose production, and has anti-inflammatory effects.
Health Claims & Evidence
Improves insulin sensitivity
Anti-inflammatory and cardioprotective effects
Reduces hepatic glucose production
Short-Term Effects
Improved insulin sensitivity, reduced inflammation.
Long-Term Effects
Research use primarily.
Side Effects
Limited data for exogenous administration.
Contraindications
Research use only.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Adiponectin and insulin sensitivity
Yamauchi et al. · Nature Medicine · 2001
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
Related Peptides
Explore the research further
Our AI Research Advisor can help you explore the evidence on Adiponectin and related peptides, and prepare an educational research summary.
Explore Research