Neuropeptide S
Neuropeptide S (NPS)
A recently discovered neuropeptide that promotes wakefulness, reduces anxiety, and enhances memory. Has a unique profile combining anxiolytic and arousal-promoting effects.
Mechanism of Action
Neuropeptide S binds to NPSR1 receptors in the brain, activating cAMP pathways that promote arousal, reduce anxiety, and enhance memory consolidation.
Health Claims & Evidence
Reduces anxiety without sedation
Promotes wakefulness and arousal
Enhances memory consolidation
Short-Term Effects
Reduced anxiety, increased arousal, potential memory enhancement.
Long-Term Effects
Research use primarily.
Side Effects
Limited human data.
Contraindications
Limited human safety data.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Neuropeptide S and anxiety
Xu et al. · Nature · 2004
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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