Phoenixin
Phoenixin (PNX)
A recently discovered neuropeptide that stimulates GnRH and LH release, reduces anxiety, and has neuroprotective properties.
Mechanism of Action
Phoenixin binds to GPR173 receptors, stimulating GnRH release and LH secretion. It also has anxiolytic effects via GABA-A receptor modulation and neuroprotective properties.
Health Claims & Evidence
Stimulates GnRH and LH release
Reduces anxiety
Neuroprotective effects
Short-Term Effects
LH stimulation, potential anxiolytic effects.
Long-Term Effects
Research use primarily.
Side Effects
Very limited human data.
Contraindications
Limited human safety data.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Phoenixin and reproductive function
Yosten et al. · Journal of Neuroendocrinology · 2013
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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