Vasopressin
Arginine Vasopressin (AVP)
A neuropeptide with dual roles as an antidiuretic hormone and a social/cognitive modulator. Intranasal vasopressin enhances memory and social recognition.
Mechanism of Action
Vasopressin binds to V1a, V1b, and V2 receptors. V2 receptor activation in kidneys produces antidiuretic effects. V1a receptor activation in the brain modulates social behavior, memory, and stress responses.
Health Claims & Evidence
Enhances memory consolidation and recall
Improves social recognition and bonding
Reduces stress and anxiety
Short-Term Effects
Improved memory consolidation, enhanced social recognition.
Long-Term Effects
Potential for sustained cognitive improvements.
Side Effects
Nasal irritation, potential water retention at high doses, headache.
Contraindications
Use with caution in cardiovascular disease. Monitor sodium levels.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Vasopressin and memory enhancement
Koob et al. · Science · 1981
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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