Neuromedin U
Neuromedin U (NMU)
A neuropeptide that reduces food intake, increases energy expenditure, and activates the stress response. Potential target for obesity treatment.
Mechanism of Action
Neuromedin U binds to NMUR1 and NMUR2 receptors. Central NMUR2 activation reduces appetite and increases energy expenditure. Peripheral NMUR1 activation stimulates smooth muscle contraction.
Health Claims & Evidence
Reduces food intake and appetite
Increases energy expenditure
Activates stress response
Short-Term Effects
Appetite suppression, increased energy expenditure.
Long-Term Effects
Research use primarily.
Side Effects
Limited human data. Potential stress activation.
Contraindications
Limited human safety data.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Neuromedin U and energy homeostasis
Hanada et al. · Nature Neuroscience · 2004
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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