TB-500
Thymosin Beta-4 (synthetic fragment)
A synthetic version of the naturally occurring peptide Thymosin Beta-4. Plays a central role in cell migration, proliferation, and tissue repair throughout the body.
Mechanism of Action
TB-500 upregulates actin — a protein essential for cell structure and movement. It promotes endothelial cell differentiation, angiogenesis, and reduces inflammation by blocking inflammatory cytokines. Its systemic distribution allows it to travel to sites of injury.
Health Claims & Evidence
Promotes systemic muscle and tissue repair
Improves flexibility and reduces scar tissue
Supports cardiovascular tissue healing
Short-Term Effects
Reduced muscle stiffness, improved range of motion, accelerated recovery from acute injuries.
Long-Term Effects
Potential for reduced chronic inflammation and improved tissue resilience. Limited long-term human data.
Side Effects
Generally well-tolerated. Mild fatigue or head rush reported by some users. Theoretical cancer risk due to angiogenic properties.
Contraindications
Avoid with active cancer or history of cancer. Not recommended during pregnancy.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Thymosin beta4 accelerates wound healing
Malinda et al. · Journal of Investigative Dermatology · 1999
Thymosin beta-4 and cardiac repair
Bock-Marquette et al. · Nature · 2004
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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