EGF
Epidermal Growth Factor (EGF)
A growth factor that stimulates cell proliferation, differentiation, and survival. Widely used in skincare for wound healing and anti-aging.
Mechanism of Action
EGF binds to EGFR receptors, activating MAPK and PI3K pathways that promote cell proliferation, migration, and survival. In skin, it stimulates keratinocyte and fibroblast activity.
Health Claims & Evidence
Promotes skin cell proliferation and wound healing
Anti-aging effects via collagen stimulation
Improves skin texture and reduces fine lines
Short-Term Effects
Improved skin texture, accelerated wound healing.
Long-Term Effects
Sustained skin improvements with consistent use.
Side Effects
Potential irritation at high concentrations. Theoretical tumor promotion risk with excessive use.
Contraindications
Use with caution in individuals with history of skin cancer.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
EGF and skin wound healing
Cohen et al. · Journal of Biological Chemistry · 1962
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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