BPC-157
Body Protection Compound-157
A synthetic pentadecapeptide derived from a protective protein found in gastric juice. Widely studied for its remarkable tissue-healing and anti-inflammatory properties.
Mechanism of Action
BPC-157 upregulates growth hormone receptors, promotes angiogenesis, and modulates nitric oxide synthesis. It accelerates healing of tendons, ligaments, muscles, and the GI tract by activating the FAK-paxillin pathway and stimulating VEGF expression.
Health Claims & Evidence
Accelerates tendon and ligament healing
Reduces systemic inflammation
Supports gut lining repair and leaky gut
May support joint health and cartilage repair
Neuroprotective and mood-modulating effects
Short-Term Effects
Reduced pain and inflammation at injury sites, improved gut comfort, faster wound closure within 1–2 weeks.
Long-Term Effects
Sustained tissue repair, potential for improved joint resilience. Long-term human safety data is limited.
Side Effects
Generally well-tolerated. Rare reports of mild nausea and dizziness. No serious adverse events documented.
Contraindications
Not recommended during pregnancy or for individuals with active cancer due to angiogenic properties.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease
Sikiric et al. · Current Pharmaceutical Design · 2016
BPC 157 and tendon healing
Chang et al. · Journal of Applied Physiology · 2011
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
Related Peptides
Explore the research further
Our AI Research Advisor can help you explore the evidence on BPC-157 and related peptides, and prepare an educational research summary.
Explore Research