CJC-1295 No DAC
CJC-1295 Without DAC (Modified GRF 1-29)
The DAC-free version of CJC-1295, also known as Modified GRF 1-29. Produces a more physiological pulsatile GH release pattern compared to the DAC version.
Mechanism of Action
CJC-1295 without DAC binds to GHRH receptors in the pituitary, stimulating a GH pulse. Without the DAC modification, it has a shorter half-life (30 minutes), producing a more natural pulsatile GH release.
Health Claims & Evidence
Stimulates pulsatile GH release
More physiological GH release pattern than DAC version
Supports body composition and recovery
Short-Term Effects
GH pulse within 30 minutes, improved sleep, mild GH-related effects.
Long-Term Effects
Gradual improvements in body composition and recovery.
Side Effects
Water retention, tingling, injection site reactions.
Contraindications
Avoid with active malignancies. Use with caution in diabetics.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Modified GRF 1-29 and GH release
Jetté et al. · Journal of Clinical Endocrinology & Metabolism · 2005
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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