Bombesin
Bombesin (BN)
An amphibian neuropeptide with mammalian analogues (GRP, NMB) that reduces food intake, stimulates GI secretions, and modulates body temperature.
Mechanism of Action
Bombesin binds to BB1 (NMB-R) and BB2 (GRP-R) receptors, reducing food intake, stimulating gastrin and CCK release, and modulating GI motility.
Health Claims & Evidence
Reduces food intake and promotes satiety
Stimulates GI secretions
Modulates body temperature
Short-Term Effects
Satiety, GI stimulation.
Long-Term Effects
Research use primarily.
Side Effects
Nausea, GI cramping.
Contraindications
Research use only.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Bombesin and food intake regulation
Gibbs et al. · Nature · 1979
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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