Hormonal & Sexual Health

Prolactin

Prolactin (PRL)

A pituitary hormone primarily known for stimulating lactation. Also has immunomodulatory, neuroprotective, and metabolic effects.

LactationImmuneReproductivePituitaryHormonal

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Category
Hormonal & Sexual Health
Research Claims
3 reviewed
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Mechanism of Action

Prolactin binds to PRLR receptors, activating JAK2-STAT5 pathways. It stimulates milk production, modulates immune function, and has neuroprotective effects.

Health Claims & Evidence

Stimulates lactation and milk production

StrongPRLR-mediated lactation is a fundamental physiological mechanism

Immunomodulatory effects

ModeratePRLR expression on immune cells; immune modulation documented

Neuroprotective effects

PreliminaryPRLR in brain; neuroprotection in some models documented

Short-Term Effects

Lactation stimulation, immune modulation.

Long-Term Effects

Research use primarily.

Side Effects

Sexual dysfunction, galactorrhea at elevated levels.

Contraindications

Not for self-administration.

This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.

Research Papers

Prolactin and immune function

Bole-Feysot et al. · Endocrine Reviews · 1998

Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.

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