Cognitive & Neurological

Neuropeptide W

Neuropeptide W (NPW)

A neuropeptide that modulates appetite, pain, and stress responses via NPBWR1 and NPBWR2 receptors. Related to Neuropeptide B.

AppetitePainStressNPBWRNeuropeptide

Quick Reference

Category
Cognitive & Neurological
Research Claims
3 reviewed
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Mechanism of Action

Neuropeptide W binds to NPBWR1 and NPBWR2 receptors, modulating appetite, pain sensitivity, and HPA axis activity.

Health Claims & Evidence

Modulates appetite and energy balance

ModerateNPBWR-mediated appetite modulation documented

Modulates pain sensitivity

Moderatepain modulation via NPBWR receptors documented

Modulates stress responses

ModerateHPA axis modulation documented

Short-Term Effects

Appetite modulation, pain sensitivity changes.

Long-Term Effects

Research use primarily.

Side Effects

Limited human data.

Contraindications

Research use only.

This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.

Research Papers

Neuropeptide W and appetite regulation

Shimomura et al. · Journal of Biological Chemistry · 2002

Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.

Related Peptides

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