INSL3
Insulin-Like Peptide 3 (INSL3 / Relaxin-like Factor)
A Leydig cell hormone that promotes testicular descent, supports bone metabolism, and has metabolic effects. Marker of Leydig cell function.
Mechanism of Action
INSL3 binds to RXFP2 receptors, promoting testicular descent during fetal development and supporting bone metabolism in adults. It is a marker of Leydig cell function and testosterone production capacity.
Health Claims & Evidence
Marker of Leydig cell function and testosterone capacity
Supports bone metabolism
Potential male fertility marker
Short-Term Effects
Potential bone metabolism effects.
Long-Term Effects
Research use primarily.
Side Effects
Limited human data.
Contraindications
Limited human safety data.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
INSL3 and Leydig cell function
Ivell et al. · Trends in Endocrinology & Metabolism · 2005
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
Related Peptides
Explore the research further
Our AI Research Advisor can help you explore the evidence on INSL3 and related peptides, and prepare an educational research summary.
Explore Research