PEG-MGF
Pegylated Mechano Growth Factor
A pegylated form of Mechano Growth Factor (MGF), an IGF-1 splice variant produced in response to muscle damage. PEGylation extends its half-life from minutes to days.
Mechanism of Action
MGF activates muscle satellite cells (stem cells) to proliferate and fuse with damaged muscle fibers, enabling muscle repair and hypertrophy. PEGylation prevents rapid degradation, allowing systemic distribution.
Health Claims & Evidence
Activates muscle satellite cells for repair and growth
Accelerates recovery from muscle damage
Supports muscle hypertrophy
Short-Term Effects
Improved muscle recovery, reduced DOMS, enhanced muscle fullness.
Long-Term Effects
Potential for sustained muscle hypertrophy with consistent cycling.
Side Effects
Limited human data. Potential for hypoglycemia. Theoretical tumor promotion risk.
Contraindications
Avoid with active malignancies. Use with caution in diabetics.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
MGF and muscle satellite cell activation
Yang et al. · Journal of Muscle Research and Cell Motility · 1996
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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