Immune & Inflammation

Vilon

Vilon (Lys-Glu)

A synthetic dipeptide bioregulator derived from the thymus. One of the simplest and most potent longevity peptides studied, Vilon demonstrates significant lifespan extension and immune restoration in animal and human research.

LongevityImmuneAnti-agingThymusDipeptide

Quick Reference

Category
Immune & Inflammation
Research Claims
5 reviewed
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Mechanism of Action

Vilon (Lys-Glu) acts as a gene expression regulator, activating genes associated with immune function and suppressing pro-apoptotic pathways. It stimulates T-lymphocyte activity, enhances natural killer (NK) cell function, and reduces chronic low-grade inflammation (inflammaging). Vilon also activates telomerase in immune cells and modulates the expression of antioxidant enzymes, contributing to reduced oxidative stress in aging tissues.

Health Claims & Evidence

Extends lifespan in animal models

Strong25–30% lifespan extension in rodent studies (Khavinson et al., multiple replications)

Restores immune function and T-cell activity in aging

Strongdocumented in both animal models and elderly human cohorts

Activates telomerase in lymphocytes

Moderatedemonstrated in cell culture studies

Reduces oxidative stress and inflammaging markers

Moderatedecreased lipid peroxidation and pro-inflammatory cytokines in aging models

Improves hematopoiesis and bone marrow function

Preliminaryobserved in aged animal models

Short-Term Effects

Enhanced immune response, improved energy and vitality, reduced susceptibility to infection.

Long-Term Effects

Cumulative immune restoration, potential telomere preservation, reduced age-related disease incidence with repeated annual courses.

Side Effects

No significant adverse effects reported in research literature. Extremely well-tolerated.

Contraindications

Limited data in pregnancy and lactation. Theoretical caution in active autoimmune conditions.

This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.

Research Papers

Dipeptide Lys-Glu increases lifespan of Drosophila melanogaster

Khavinson VKh et al. · Bulletin of Experimental Biology and Medicine · 2012

Peptide regulation of aging

Khavinson VKh · Neuroendocrinology Letters · 2002

Effect of Vilon on the immune system of aging mice

Morozov VG et al. · Gerontology · 1999

Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.

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