TSH
Thyroid-Stimulating Hormone (TSH / Thyrotropin)
The pituitary hormone that stimulates thyroid hormone production. Recombinant TSH (Thyrogen) is FDA-approved for thyroid cancer management.
Mechanism of Action
TSH binds to TSHR receptors on thyroid follicular cells, stimulating thyroid hormone synthesis and secretion. It also promotes thyroid cell growth.
Health Claims & Evidence
Stimulates thyroid hormone production
Diagnostic tool for thyroid cancer
Stimulates radioiodine uptake in thyroid cancer
Short-Term Effects
Thyroid hormone elevation, radioiodine uptake stimulation.
Long-Term Effects
Diagnostic use only.
Side Effects
Nausea, headache, fatigue.
Contraindications
Use with caution in cardiovascular disease.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Recombinant TSH in thyroid cancer management
Haugen et al. · Journal of Clinical Endocrinology & Metabolism · 1999
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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