HGF
Hepatocyte Growth Factor (HGF)
A pleiotropic growth factor that promotes liver regeneration, muscle repair, angiogenesis, and neuroprotection.
Mechanism of Action
HGF binds to the Met receptor, activating MAPK and PI3K pathways. It promotes hepatocyte proliferation, muscle satellite cell activation, angiogenesis, and neuronal survival.
Health Claims & Evidence
Promotes liver regeneration
Supports muscle repair via satellite cell activation
Neuroprotective effects
Short-Term Effects
Liver regeneration, muscle repair support.
Long-Term Effects
Research use primarily.
Side Effects
Potential tumor promotion with excessive Met activation.
Contraindications
Use with caution in individuals with active cancer.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
HGF and liver regeneration
Michalopoulos et al. · Cancer Research · 1984
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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