LH
Luteinizing Hormone (LH)
The pituitary hormone that triggers ovulation in females and stimulates testosterone production in males. Used clinically for fertility treatment.
Mechanism of Action
LH binds to LHR receptors on Leydig cells (stimulating testosterone) and granulosa/theca cells (triggering ovulation). It is the downstream effector of GnRH pulsatile signaling.
Health Claims & Evidence
Stimulates testosterone production in males
Triggers ovulation in females
Fertility treatment
Short-Term Effects
Testosterone elevation (males), follicle maturation and ovulation (females).
Long-Term Effects
Fertility treatment outcomes.
Side Effects
Ovarian hyperstimulation syndrome (females), gynecomastia (males at high doses).
Contraindications
Ovarian cysts, hormone-sensitive cancers.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
LH and reproductive function
Themmen et al. · Endocrine Reviews · 2000
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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