Activin A
Activin A
A TGF-beta family member that stimulates FSH secretion, modulates inflammation, and regulates bone metabolism. Follistatin is its natural antagonist.
Mechanism of Action
Activin A binds to activin receptors (ACVR1B/2A/2B), stimulating FSH secretion, promoting inflammatory responses, and modulating bone formation. Follistatin neutralizes activin A.
Health Claims & Evidence
Stimulates FSH secretion
Modulates inflammatory responses
Regulates bone metabolism
Short-Term Effects
FSH stimulation, inflammatory modulation.
Long-Term Effects
Research use primarily.
Side Effects
Pro-inflammatory effects at high doses.
Contraindications
Research use only.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Activin A and FSH regulation
Vale et al. · Nature · 1986
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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