ANP
Atrial Natriuretic Peptide (ANP)
A cardiac hormone produced by the atria in response to increased atrial pressure. Regulates blood pressure, blood volume, and sodium balance.
Mechanism of Action
ANP binds to natriuretic peptide receptor A (NPR-A), activating cGMP pathways that cause vasodilation, natriuresis, and inhibition of the renin-angiotensin-aldosterone system.
Health Claims & Evidence
Reduces blood pressure and blood volume
Inhibits RAAS system
Cardioprotective effects
Short-Term Effects
Rapid blood pressure reduction, natriuresis.
Long-Term Effects
Research use only.
Side Effects
Hypotension, headache.
Contraindications
Hypotension. Not for self-administration.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Atrial natriuretic peptide and cardiovascular regulation
de Bold et al. · Life Sciences · 1981
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
Related Peptides
Explore the research further
Our AI Research Advisor can help you explore the evidence on ANP and related peptides, and prepare an educational research summary.
Explore Research