Omentin-1
Omentin-1 (Intelectin-1)
An adipokine produced by visceral adipose tissue with insulin-sensitizing and anti-inflammatory properties. Levels are reduced in obesity and metabolic syndrome.
Mechanism of Action
Omentin-1 binds to an unidentified receptor, activating Akt pathways that improve insulin sensitivity. It also has anti-inflammatory effects via NF-kB inhibition and vasodilatory properties.
Health Claims & Evidence
Improves insulin sensitivity
Anti-inflammatory effects
Cardioprotective effects
Short-Term Effects
Improved insulin sensitivity, anti-inflammatory effects.
Long-Term Effects
Research use primarily.
Side Effects
Limited human data.
Contraindications
Limited human safety data.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Omentin-1 and insulin sensitivity
Yang et al. · Journal of Clinical Endocrinology & Metabolism · 2006
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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