Follistatin-344
Follistatin-344 (FST-344)
A naturally occurring protein that inhibits myostatin and activin, promoting muscle growth. The 344 isoform is the most commonly used in research.
Mechanism of Action
Follistatin-344 binds and neutralizes myostatin, activin, and other TGF-beta family members. It also promotes FSH suppression and has effects on reproductive function.
Health Claims & Evidence
Inhibits myostatin and promotes muscle growth
Enhances strength and athletic performance
Potential for muscle wasting disease treatment
Short-Term Effects
Potential rapid muscle mass increase. Effects may be dramatic in short cycles.
Long-Term Effects
Limited data. Theoretical sustained muscle hypertrophy.
Side Effects
Very limited human data. Theoretical risks include reproductive effects (FSH suppression).
Contraindications
Not recommended for women of reproductive age. Very limited human safety data.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
Follistatin and myostatin inhibition
Lee et al. · Proceedings of the National Academy of Sciences · 2001
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
Related Peptides
Explore the research further
Our AI Research Advisor can help you explore the evidence on Follistatin-344 and related peptides, and prepare an educational research summary.
Explore Research