hCG
Human Chorionic Gonadotropin (hCG)
A placental hormone with LH-like activity. Used clinically for fertility treatment and in TRT protocols to maintain testicular function.
Mechanism of Action
hCG binds to LHR receptors (same as LH), stimulating testosterone production in males and supporting corpus luteum function in females. It has a longer half-life than LH.
Health Claims & Evidence
Stimulates testosterone production
Maintains testicular function during TRT
Fertility treatment in males and females
Short-Term Effects
Testosterone elevation, testicular volume maintenance.
Long-Term Effects
Sustained testicular function preservation during TRT.
Side Effects
Gynecomastia (estrogen conversion), acne, potential desensitization with chronic use.
Contraindications
Hormone-sensitive cancers. Androgen-dependent conditions.
This profile is provided for educational research only. It is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Verify primary sources and consult a qualified healthcare professional for medical decisions.
Research Papers
hCG in male hypogonadism
Coviello et al. · Journal of Clinical Endocrinology & Metabolism · 2005
Educational research only. This profile is not a treatment recommendation or dosing guide. Human evidence, safety information and regulatory status vary by substance. Consult a qualified healthcare professional for medical decisions.
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